Dr. Hui Lijian
惠利健
Professor; Principal Investigator; Director of the State Key Laboratory of Cell Biology
Where they practice, who they consult.
- Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS-SIBS), Shanghai
- 25+ years in liver cell biology and regenerative medicine
- English, Mandarin
What they personally lead.
Training and recognition
Led the team that first reported transdifferentiation of human fibroblasts directly into functional hepatocyte-like cells (hiHeps) without going through a pluripotent intermediate, published in Cell Stem Cell; advanced hiHep-based bioartificial liver systems through preclinical studies and into investigational clinical use for acute-on-chronic liver failure in collaboration with hospital partners; advanced liver organoid platforms for drug testing and disease modeling; serves on the editorial boards of regenerative medicine journals and in scientific advisory roles for Chinese Academy of Sciences cell-therapy initiatives; recipient of CAS Outstanding Achievement awards <!-- TODO: needs second source -->
What to expect
Dr. Hui's program is research- and trial-focused. Patients with severe acute liver failure or decompensated cirrhosis interested in bioartificial liver support studies should be referred through tertiary hepatology centers participating in the trials (commonly affiliated Shanghai hospitals); direct walk-in clinical care with Dr. Hui is not the model. Standard of care for end-stage liver disease in China remains liver transplantation where eligible.
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