Dr. Deng Hongkui
邓宏魁
Professor; Principal Investigator; Boya Chair Professor at Peking University
Where they practice, who they consult.
- Peking University Stem Cell Research Center, College of Life Sciences and Peking University Health Science Center, Beijing
- 30+ years in stem cell biology and chemical biology
- English, Mandarin
What they personally lead.
Training and recognition
Led the team that first reported chemical reprogramming of somatic cells to pluripotency using small-molecule cocktails, eliminating the need for transgenic factors — a methodology highlighted in Science and Cell Stem Cell; co-led the first-in-human clinical case using autologous chemically induced pluripotent stem cell-derived pancreatic islets to treat a patient with type 1 diabetes, with the case report published in Cell in 2024; principal investigator on a registered ChiCTR clinical study evaluating CiPSC-derived islet transplantation; recipient of multiple national-level science awards; published extensively in Cell, Nature, and Cell Stem Cell <!-- TODO: needs second source -->
What to expect
Dr. Deng's work is principally translational research conducted under formally registered clinical study protocols, not standard clinical care. Patients with type 1 diabetes interested in islet cell trials should contact the Peking University Stem Cell Research Center or affiliated hospital trial coordinators (typically at Peking University Third Hospital or Tianjin First Central Hospital, depending on the specific trial). Eligibility is restrictive, immunosuppression is generally still required for allogeneic protocols, and long-term safety data is still being collected.
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